Nitric Oxide and Blood Sugar

Diabetes NeedleDiabetes is a worldwide epidemic. In the U.S alone it is estimated that some 26 million people have diagnosed or undiagnosed diabetes. Around 80 million are pre-diabetic. The main complications surrounding this health problem are:

  • Heart attack
  • Stroke
  • High blood pressure
  • Blindness
  • Kidney disease
  • Neuropathy
  • Amputation

Everything mentioned above can be improved by maintaining healthy levels of Nitric Oxide (NO). To make NO you need the semi-essential amino acid called: L-arginine. L-arginine helps maintain healthy blood sugar in two ways. First, L-arginine is an essential nutrient for your pancreas to make insulin. Insulin is the hormone that binds to sugar in your blood and into your cells to make energy. Second,

L-arginine converts into Nitric Oxide which help your cells to be more sensitive to the insulin your body produces. And the reason many folks become diabetic is due to insulin resistivity (aka., insulin desensitivity, metabolic disorder, Syndrome X, diabesity, etc).

diabetes test stripsAs mentioned, the reason diabetics want to increase their NO (all diabetics are deficient in NO) is they severely reduce their chance for the health complications listed above. In fact, one diabetic specialist used to send 250 patients a year to cardiologists. Since using L-arginine, L-citrulline, antioxidants and vitamin D with his patients he sends maybe one per year. He has been using L-arginine with his diabetic patients for close to 20 years. Get this… Since using it he has not had even one patient to die of a heart attack or stoke! That is unheard of.

Research on arginine/nitric oxide and blood sugar:

  1. Paolo Tessari, Diego Cecchet, Carlo Artusi, Monica Vettore, Renato Millioni, Mario Plebani, Lucia Puricelli, and Monica Vedovato, Roles of Insulin, Age, and Asymmetric Dimethylarginine on Nitric Oxide Synthesis In Vivo, Diabetes 2013;62:2699-2708.
  2. Advanced Glycosylation Products Quench Nitric Oxide and Mediate Defective Endothelium-dependent Vasodilatation in Experimental Diabetes; Richard Bucala,Kevin J. Tracey,* and Anthony Cerami Laboratory of Medical Biochemistry, The Rockefeller University, New York 10021;and *Division of Neurosurgery, Cornell University Medical College, New York 10021
  3. Piatti PM, Monti LD, Valsecchi G, et al. Long term oral L-arginine administration improves peripheral and hepatic insulin sensitivity in type 2 diabetes. Diabetes Care 2001 MAY;24(5):875-80
  4. Giugliana D, et al. Vascular effects of acute hyperglycemia are reversed by L-arginine. Circulation 1997; 95(7):1783-90
  5. Mohan IK, Cas UN. Effects of L-arginine-nitric oxide system on chemical induced diabetes mellitus. Free Radic Biol Med 1998 Nov 1;25(7):757-65
  6. Mendez JD, Balderas F. Regulation of hyperglycemia and dyslipidemia by exogenous L-arginine in Diabetic rats. Biochemie 2001 May;83(5):453-8

“I have been diagnosed with adult onset diabetes.  My blood sugar would really swing despite taking medications.  A friend suggested I start taking a double dose of the arginine drink she was taking.  My blood sugar did go down.  My doctor took me off my Metformin.  Not only that, my pain went away, I started to sleep better and now I have the energy of the energizer bunny!  I feel like I am on the fast track to health.”

Reginald